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VU591 hydrochloride 是选择性的肾外髓钾通道抑制剂,IC50为 0.24 μM。
VU591 hydrochloride 是选择性的肾外髓钾通道抑制剂,IC50为 0.24 μM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 286 | 现货 | |
2 mg | ¥ 417 | 现货 | |
5 mg | ¥ 696 | 现货 | |
10 mg | ¥ 1,120 | 现货 | |
25 mg | ¥ 2,380 | 现货 | |
50 mg | ¥ 3,970 | 现货 | |
100 mg | ¥ 5,500 | 现货 | |
500 mg | ¥ 10,900 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 762 | 现货 |
产品描述 | VU591 hydrochloride is a selective renal outer medullary potassium channel (Kir1.1, ROMK) antagonist (IC50:0.24 μM). Thought to block the intracellular pore of the Kir1.1 channel. Exhibits no effect on Kir7.1 at concentrations up to 10 μM; does not inhibit Kir2.1, Kir2.3 or Kir4.1. Displays similar potency to VU 590 |
靶点活性 | ROMK:0.24 μM |
分子量 | 404.76 |
分子式 | C16H13ClN6O5 |
CAS No. | 1315380-70-1 |
Smiles | Cl.[O-][N+](=O)c1ccc2nc(COCc3nc4ccc(cc4[nH]3)[N+]([O-])=O)[nH]c2c1 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
溶解度信息 | DMSO: 4.33 mg/mL (10.71 mM), Sonication is recommended. | ||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||
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